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1.
Chaos Solitons Fractals ; 144: 110678, 2021 Mar.
Article in English | MEDLINE | ID: covidwho-1068882

ABSTRACT

In this paper a fractional optimal control problem was formulated for the outbreak of COVID-19 using a mathematical model with fractional order derivative in the Caputo sense. The state and co-state equations were given and the best strategy to significantly reduce the spread of COVID-19 infections was found by introducing two time-dependent control measures, u 1 ( t ) (which represents the awareness campaign, lockdown, and all other measures that reduce the possibility of contacting the disease in susceptible human population) and u 2 ( t ) (which represents quarantine, monitoring and treatment of infected humans). Numerical simulations were carried out using RK-4 to show the significance of the control functions. The exposed population in susceptible population is reduced by the factor ( 1 - u 1 ( t ) ) due to the awareness and all other measures taken. Likewise, the infected population is reduced by a factor of ( 1 - u 2 ( t ) ) due to the monitoring and treatment by health professionals.

2.
Comput Math Methods Med ; 2020: 5248569, 2020.
Article in English | MEDLINE | ID: covidwho-883419

ABSTRACT

In this paper, we developed a model that suggests the use of robots in identifying COVID-19-positive patients and which studied the effectiveness of the government policy of prohibiting migration of individuals into their countries especially from those countries that were known to have COVID-19 epidemic. Two compartmental models consisting of two equations each were constructed. The models studied the use of robots for the identification of COVID-19-positive patients. The effect of migration ban strategy was also studied. Four biologically meaningful equilibrium points were found. Their local stability analysis was also carried out. Numerical simulations were carried out, and the most effective strategy to curtail the spread of the disease was shown.


Subject(s)
Betacoronavirus , Coronavirus Infections/prevention & control , Models, Biological , Pandemics/prevention & control , Pneumonia, Viral/prevention & control , COVID-19 , COVID-19 Testing , Clinical Laboratory Techniques/instrumentation , Clinical Laboratory Techniques/statistics & numerical data , Computational Biology , Computer Simulation , Coronavirus Infections/diagnosis , Coronavirus Infections/epidemiology , Coronavirus Infections/transmission , Humans , Mathematical Concepts , Models, Statistical , Pandemics/statistics & numerical data , Pneumonia, Viral/epidemiology , Pneumonia, Viral/transmission , Robotics/instrumentation , Robotics/statistics & numerical data , SARS-CoV-2 , Travel
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